pentobarbital will decrease the extent or result of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can lower panobinostat concentrations by ~70% and produce remedy